NASAL DRUG DELIVERY SYSTEM: A ROUTE FOR BRAINE TARGETTING
نویسندگان
چکیده
منابع مشابه
Nasal Drug Delivery: A Potential Route for Brain Targeting
Present review highlights the potential of nasal mucosa as an administration route for targeting the central nervous system, the brain. Targeted drug delivery seeks to concentrate the medication in the tissues of interest while reducing the relative concentration of medication in the remaining tissues. Thus improving efficacy of the drug and reducing side effects. The nasal mucosa when compared...
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Currently, Nasal drug delivery has been recognized as a very promising route for delivery of therapeutic compounds including biopharmaceuticals 1 . Nasal administration is a logical choice for topical nasal treatments such as antihistamines and corticosteroids. The nasal mucosa has also received attention as a viable means of systemic administration of analgesics, sedatives, hormones, cardiovas...
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Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine wh...
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Copyright: © 2016 Misra A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Corresponding author: Ambikanandan Misra, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara 3900...
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INTRODUCTION Certain drugs are delivered to the nasal cavity because their intended site of action. These are administrated as nasal drops or sprays for a local effect. Such drugs in clinical use include decongestants, antibiotics and mucolytics. The nasal cavity may also be exploited as a route of entry into the systematic circulation, either because the absorption profile of the drug is appro...
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ژورنال
عنوان ژورنال: World Journal of Pharmaceutical Research
سال: 2017
ISSN: 2277-7105
DOI: 10.20959/wjpr20179-9096